Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717828 | 0.97 | HMGCR (0.41) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| SCHEMBL41886 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1092821 | 0.94 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| Hydrochloric Acid SCHEMBL28883817 | 0.94 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| Methane SCHEMBL27575418 | 0.94 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| Acetic Acid SCHEMBL20839531 | 0.92 | CTH (0.42) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| SCHEMBL28060901 | 0.87 | DPP4 (0.35) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| Hydrogen Sulfide SCHEMBL27991575 | 0.85 | EGLN1 (0.37) | HMGCRCHRM1TBXA2RADRA1ACTH | |
| SCHEMBL14805819 | 0.83 | EGLN1 (0.40) | CTHDPP4EGLN1ALDH1A1LMNA | |
| SCHEMBL8654274 | 0.83 | DPP4 (0.33) | HMGCRCHRM1TBXA2RADRA1ACTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188832-B1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | YEDA RES & DEV (IL) | 2023-10-04 | — | — | EP | disclosed |
| US-20170283447-A1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-10-05 | — | — | US | disclosed |
| EP-3188832-A1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | Yeda Research and Development Co., Ltd. (IL) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016035080-A1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283447-A1 | RUTHENIUM COMPLEXES AND THEIR USES AS CATALYSTS IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND RELATED REACTIONS | ADH1A, ADH1C, ADH5 | HMGCR 4154/4885CHRM1 632/4885TBXA2R 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.