SCHEMBL17563157

SCHEMBL17563157

FC(F)(F)c1cc(C(F)(F)F)c(-n2c3ccccc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)c(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PPARG P37231 3/20 0.35
PPARA Q07869 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
AR P10275 4/20 0.34
MPI P34949 1/20 0.34
PHOSPHO1 Q8TCT1 1/20 0.34
PTGES O14684 2/20 0.33
GRM4 Q14833 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PLA2G10 O15496 1/20 0.33
GSR P00390 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16127317 0.89 KIF11 (0.35) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL17563165 0.88 KDM4E (0.42) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL17563140 0.84 KDM4E (0.36) KIF11KDM4EATML3MBTL1AR
SCHEMBL17950238 0.83 KIF11 (0.44) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL16127328 0.83 KIF11 (0.41) KIF11KDM4EATML3MBTL1GRM4
SCHEMBL45634 0.83 L3MBTL1 (0.50) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL22140541 0.83 L3MBTL1 (0.48) KIF11KDM4EATML3MBTL1AR
SCHEMBL24510808 0.82 KIF11 (0.40) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL17381252 0.82 KDM4E (0.44) KIF11KDM4EATML3MBTL1PPARG
SCHEMBL17381337 0.82 KDM4E (0.44) KIF11KDM4EATML3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3375785-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-08-05 EP disclosed
US-10193079-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-01-29 US disclosed
EP-2976329-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-06-27 EP disclosed
US-20160072076-A1 MATERIALS FOR ELECTRONIC DEVICES UDC IRELAND LIMITED (IE) 2016-03-10 US disclosed
US-20160072076-A1 MATERIALS FOR ELECTRONIC DEVICES UDC IRELAND LIMITED (IE) 2016-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160072076-A1 MATERIALS FOR ELECTRONIC DEVICES AOC3, AOC2, AOC1 KIF11 939/4885KDM4E 2957/4885ATM 896/4885
US-10193079-B2 Materials for electronic devices AOC3, AOC2, AOC1 KIF11 939/4885KDM4E 2957/4885ATM 896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.