Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 17/20 | 0.50 |
| ▸ | NPC1 | O15118 | 15/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311967 | 0.94 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17951436 | 0.93 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14465695 | 0.92 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL173684 | 0.92 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL502474 | 0.90 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14466355 | 0.90 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL175637 | 0.85 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14466543 | 0.84 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17955168 | 0.84 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14465523 | 0.84 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609258-B2 | Light emitting devices and compositions | NITTO DENKO CORPORATION (JP) | 2013-12-17 | — | — | US | claimed |
| US-8597803-B2 | Light emitting devices and compositions | NITTO DENKO CORPORATION (JP) | 2013-12-03 | — | — | US | claimed |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2012-12-06 | — | — | US | claimed |
| US-20120273765-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2012-11-01 | — | — | US | claimed |
| US-20090179552-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-07-16 | — | — | US | claimed |
| WO-2009064661-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-05-22 | — | — | WO | claimed |
| US-20090066234-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-03-12 | — | — | US | claimed |
| WO-2009006550-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-01-08 | — | — | WO | claimed |
| WO-2012030421-A1 | DEVICES AND METHODS | QD VISION, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066234-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | MAP1LC3A, MAP1LC3C, CRY1 | RAB9A 962/4885NPC1 3835/4885SMN1; SMN2 2322/4885 |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | ILK, CRY1, IK | RAB9A 512/4885NPC1 3013/4885SMN1; SMN2 2301/4885 |
| US-20090179552-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | CYBA, LIMA1, CRY1 | RAB9A 850/4885NPC1 3302/4885SMN1; SMN2 2606/4885 |
| US-20120273765-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | CYBA, LIMA1, CRY1 | RAB9A 850/4885NPC1 3302/4885SMN1; SMN2 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.