Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756507 | 1.00 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL32677437 | 0.96 | ACE (0.44) | ACERENKDM4EF2LMNA | |
| SCHEMBL30051863 | 0.92 | ACE (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL30051521 | 0.89 | KMT2A (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL30008142 | 0.87 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL29351055 | 0.87 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL29512282 | 0.87 | CAPN1 (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL30957276 | 0.86 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL30553722 | 0.86 | CALCRL (0.42) | ACERENKDM4EF2LMNA | |
| Trifluoroacetic Acid SCHEMBL7313892 | 0.86 | ELANE (0.47) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096173-B1 | Method of measuring glycolated hemoglobin A1C, enzyme to be used therefor and process for producing the same | ASAHI KASEI PHARMA CORP (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-7943337-B2 | Method for screening a protease | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1626088-B1 | METHOD OF MEASURING GLYCOLATED HEMOGLOBIN A1C, ENZYME TO BE USED THEREFOR AND PROCESS FOR PRODUCING THE SAME | ASAHI KASEI PHARMA CORP (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-20090317851-A1 | HEMOGLOBIN A1C DETERMINATION METHOD, ENZYME TO BE USED THEREFOR, AND PRODUCTION METHOD THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |
| US-7588910-B2 | Hemoglobin A1c determination method, enzyme to be used therefor, and production method thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-15 | — | — | US | disclosed |
| EP-2096173-A1 | Method of measuring glycolated hemoglobin A1C, enzyme to be used therefor and process for producing the same | Asahi Kasei Pharma Corporation (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20080113381-A1 | Hemoglobin A1c Determination Method, Enzyme to be Used therefor, and Production Method Thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-05-15 | — | — | US | disclosed |
| EP-1626088-A1 | METHOD OF MEASURING GLYCOLATED HEMOGLOBIN A1C, ENZYME TO BE USED THEREFOR AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Pharma Corporation (JP) | 2006-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113381-A1 | Hemoglobin A1c Determination Method, Enzyme to be Used therefor, and Production Method Thereof | HBB, HBZ, ANPEP | ACE 281/4885REN 337/4885KDM4E 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.