SCHEMBL1756525

SCHEMBL1756525

Fc1c(F)c(Cl)c(Cl)c(Cl)c1F

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1756530 0.95 CES2 (0.38) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL1756501 0.95 CES2 (0.38) CES2CES1
SCHEMBL219009 0.86 CES2 (0.38) CES2CES1
SCHEMBL1756500 0.86 CES2 (0.38) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL7214722 0.86 CES2 (0.38) CES2CES1
SCHEMBL1942159 0.82 CES2 (0.36) CES2CES1
Magnesium SCHEMBL30578300 0.82 CES2 (0.36) CES2CES1
SCHEMBL10589276 0.82 CES2 (0.36) CES2CES1
SCHEMBL4449502 0.82 CES2 (0.36) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL4345041 0.80 CES2 (0.33) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944564-B9 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2005-01-19 EP claimed
EP-0944564-B1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2002-03-20 EP claimed
EP-0944564-A1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORPORATION (US) 1999-09-29 EP claimed
US-5824827-A Halogen exchange reactions ALBEMARLE CORPORATION (US) 1998-10-20 US claimed
WO-1998022413-A1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORPORATION (US) 1998-05-28 WO claimed
CN-119137244-A Lubricant for magnetic recording medium 株式会社力森诺科 2024-12-13 CN disclosed
US-20240409489-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER RESONAC CORPORATION (JP) 2024-12-12 US disclosed
US-20240400757-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER RESONAC CORPORATION (JP) 2024-12-05 US disclosed
WO-2024214529-A1 MAGNETIC RECORDING MEDIUM LUBRICANT 株式会社レゾナック 2024-10-17 WO disclosed
CN-118139839-A Process for producing fluorinated polyether 株式会社力森诺科 2024-06-04 CN disclosed
CN-118055920-A Process for producing fluorinated polyether 株式会社力森诺科 2024-05-17 CN disclosed
WO-2023058753-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER 株式会社レゾナック 2023-04-13 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
US-4734503-A Catalytic transhalogenation of haloaromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-29 US disclosed
EP-0233035-A1 Catalytic transhalogenation of haloaromatics E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-19 EP disclosed
US-4680406-A Process for fluorinating halogenated organo-compounds THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409489-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER MRPL21, RPS4X, MLX CES2 3421/4885CES1 3032/4885MEN1 721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.