SCHEMBL1756500

SCHEMBL1756500

Fc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AHR P35869 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449502 0.95 CES2 (0.36) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL5848856 0.95 CES2 (0.33) CES2CES1
SCHEMBL1756530 0.90 CES2 (0.38) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL1756525 0.86 CES2 (0.43) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL4453076 0.84 CES2 (0.33) CES2CES1
SCHEMBL1756501 0.80 CES2 (0.38) CES2CES1
SCHEMBL11715348 0.79 TSHR (0.62) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL10589276 0.76 CES2 (0.36) CES2CES1
SCHEMBL18568549 0.76
SCHEMBL9774772 0.76 CES2 (0.32) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725183-B A kind of environment-friendly treatment method of hexachloro-benzene 巨化集团技术中心 2017-12-22 CN claimed
CN-104725183-A Environment-friendly treatment method of hexachlorobenzene JUHUA GROUP TECHNOLOGY CT 2015-06-24 CN claimed
CN-217265503-U Pentafluorophenol's synthesis system 内蒙古蓝科生物科技有限公司 2022-08-23 CN disclosed
CN-217265503-U Pentafluorophenol's synthesis system 内蒙古蓝科生物科技有限公司 2022-08-23 CN disclosed
CN-104725183-B A kind of environment-friendly treatment method of hexachloro-benzene 巨化集团技术中心 2017-12-22 CN disclosed
CN-105016983-A Preparation method of pentafluorophenol KINGCHEM LIAONING CHEMICAL CO LTD 2015-11-04 CN disclosed
CN-104725183-A Environment-friendly treatment method of hexachlorobenzene JUHUA GROUP TECHNOLOGY CT 2015-06-24 CN disclosed
US-7943257-B2 Electrolyte solvent and rechargeable lithium battery SAMSUNG SDI CO., LTD. (KR) 2011-05-17 US disclosed
CN-101160278-B Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives BASF AG 2011-02-09 CN disclosed
CN-101168493-B Preparation method for fluorochlorobenzene CHINA PETROLEUM CHEMICAL CO LTD 2010-08-18 CN disclosed
US-20100104949-A1 Electrolyte and rechargeable lithium battery YAMAGUCHI TAKITARO 2010-04-29 US disclosed
US-5824827-A Halogen exchange reactions ALBEMARLE CORPORATION (US) 1998-10-20 US disclosed
US-5789631-A Production of perhalobenzenes ALBEMARLE CORPORATION (US) 1998-08-04 US disclosed
WO-1998022413-A1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORPORATION (US) 1998-05-28 WO disclosed
US-5315043-A Potassium, cesium, rubidium fluorides and hydrofluoric acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-24 US disclosed
EP-0583705-A1 Process for the preparation of 2,3,4-trichloro-5-fluoro-benzoylchloride BAYER AG (DE) 1994-02-23 EP disclosed
US-4734503-A Catalytic transhalogenation of haloaromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-29 US disclosed
EP-0233035-A1 Catalytic transhalogenation of haloaromatics E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-19 EP disclosed
US-4680406-A Process for fluorinating halogenated organo-compounds THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed
US-3852365-A PREPARATION OF PERCHLOROFLUOROBENZENES DU PONT 1974-12-03 US disclosed