SCHEMBL1756530

SCHEMBL1756530

Fc1c(F)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AHR P35869 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1756525 0.95 CES2 (0.43) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL1756501 0.90 CES2 (0.38) CES2CES1
SCHEMBL1756500 0.90 CES2 (0.38) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL4449502 0.86 CES2 (0.36) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL4345041 0.84 CES2 (0.33) CES2CES1
SCHEMBL5848856 0.84 CES2 (0.33) CES2CES1
SCHEMBL219009 0.80 CES2 (0.38) CES2CES1
SCHEMBL7214722 0.80 CES2 (0.38) CES2CES1
SCHEMBL11705311 0.79 TSHR (0.53) CES2CES1MEN1ALDH1A1LMNA
SCHEMBL7193602 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725183-B A kind of environment-friendly treatment method of hexachloro-benzene 巨化集团技术中心 2017-12-22 CN claimed
CN-104725183-A Environment-friendly treatment method of hexachlorobenzene JUHUA GROUP TECHNOLOGY CT 2015-06-24 CN claimed
CN-104725183-B A kind of environment-friendly treatment method of hexachloro-benzene 巨化集团技术中心 2017-12-22 CN disclosed
CN-104725183-A Environment-friendly treatment method of hexachlorobenzene JUHUA GROUP TECHNOLOGY CT 2015-06-24 CN disclosed
US-7943257-B2 Electrolyte solvent and rechargeable lithium battery SAMSUNG SDI CO., LTD. (KR) 2011-05-17 US disclosed
US-20100104949-A1 Electrolyte and rechargeable lithium battery YAMAGUCHI TAKITARO 2010-04-29 US disclosed
US-7595426-B2 Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2009-09-29 US disclosed
US-20080214878-A1 Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US disclosed
US-7148383-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2006-12-12 US disclosed
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same LESLIE THOMAS M 2005-10-27 US disclosed
US-6933412-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2005-08-23 US disclosed
US-5824827-A Halogen exchange reactions ALBEMARLE CORPORATION (US) 1998-10-20 US disclosed
WO-1998022413-A1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORPORATION (US) 1998-05-28 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
US-4680406-A Process for fluorinating halogenated organo-compounds THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed
US-3852365-A PREPARATION OF PERCHLOROFLUOROBENZENES DU PONT 1974-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same CRY2, SOS2, CRYZ CES2 3673/4885CES1 3199/4885MEN1 4251/4885
US-20080214878-A1 Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives FLNB, AFF1, AFF2 CES2 52/4885CES1 324/4885MEN1 3209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.