Triphenylene

Triphenylene

SCHEMBL1756536

O=P(O)(O)O.c1ccc2c(c1)c1ccccc1c1ccccc21

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Triphenylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
ACP3 P15309 2/20 0.44
SRC P12931 2/20 0.43
CFTR P13569 1/20 0.43
PTK2B Q14289 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
IDO1 P14902 1/20 0.42
PTPN1 P18031 1/20 0.42
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
CA12 O43570 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP14 P50281 1/20 0.40
CA14 Q9ULX7 1/20 0.40
PADI4 Q9UM07 1/20 0.40
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27815907 0.82 CYP3A4 (0.43) CA2CA4CA5AACP3SRC
Phenanthrene SCHEMBL3793701 0.82 ALDH1A1 (0.67) CA2ACP3PTK2BL3MBTL1TSHR
Naphthalene SCHEMBL19062554 0.79 CYP2A6 (0.57) CA2CA4CA5AACP3SRC
Naphthalene SCHEMBL1680172 0.79 CYP2A6 (0.57) CA2CA4CA5AACP3SRC
Naphthalene SCHEMBL3796240 0.79 CYP2A6 (0.57) CA2CA4CA5AACP3SRC
Naphthalene SCHEMBL30445823 0.79 CYP2A6 (0.57) CA2CA4CA5AACP3SRC
Naphthalene SCHEMBL30423233 0.79 CYP2A6 (0.57) CA2CA4CA5AACP3SRC
Phosphoric Acid SCHEMBL4104685 0.79 CA2 (0.50) CA2CA4CA5ASRCCFTR
Phosphoric Acid SCHEMBL14931822 0.79 MEN1 (0.50) CA2CA4CA5ASRCCFTR
Phosphoric Acid SCHEMBL27648570 0.79 MEN1 (0.50) CA2CA4CA5ASRCCFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114149570-A Narrow molecular weight polycaprolactone dihydric alcohol with molecular weight of 2000 and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2022-03-08 CN claimed
JP-63215742-A None JP disclosed
CN-117120484-A Polymerization catalyst for olefin polymer 日本聚化株式会社 2023-11-24 CN disclosed
CN-114149570-A Narrow molecular weight polycaprolactone dihydric alcohol with molecular weight of 2000 and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2022-03-08 CN disclosed
CN-114149570-A Narrow molecular weight polycaprolactone dihydric alcohol with molecular weight of 2000 and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2022-03-08 CN disclosed
US-9725591-B2 Reinforced resin composition for plating base, molded article, and electroplated component UMG ABS, LTD. (JP) 2017-08-08 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-20130222720-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE KONICA MINOLTA , INC. (JP) 2013-08-29 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-20040096594-A1 Phase difference plate comprising polymer film containing compound having rod- shaped molecular structure FUJIFILM CORPORATION (JP) 2004-05-20 US disclosed
US-20040017364-A1 Inner type touch panel, process for producing the same and display unit FUJI PHOTO FILM CO., LTD. 2004-01-29 US disclosed
EP-1369713-A1 PHASE DIFFERENCE PLATE COMPRISING POLYMER FILM CONTAINING COMPOUND HAVING ROD-SHAPED MOLECULAR STRUCTURE FUJI PHOTO FILM CO., LTD. (JP) 2003-12-10 EP disclosed
CN-1449427-A Halogen-free flame-retardant epoxy resin composition, halogen-free flame-retardant epoxy resin composition for build-up multilayer board, prepreg, copper clad laminate, printed circuit board, copper clad resin film, carrier resin film, build-up laminate, and build-up multilayer board KYOCERA CHEM CORP (JP) 2003-10-15 CN disclosed
US-20030148107-A1 Halogen-free nonflammable epoxy resin composition, halogen-free nonfammable epoxy resin composition for build-up type multi-layer board, prepreg, copper-clad laminate, printed wiring board, copper foil-attached resin film, carrier-attached resin film, build-up type laminate, and build-up type multi-layer board KYOCERA CHEMICAL CORPORATION 2003-08-07 US disclosed
US-6089278-A Tube for fuel transportation NITTA MOORE COMPANY (JP) 2000-07-18 US disclosed
EP-0359469-B1 An electroless plating-susceptive, fire retardant polyphenylene ether resin ASAHI CHEMICAL IND (JP) 1995-11-08 EP disclosed
US-4966814-A LEND WITH A GRAFT RUBBER COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-30 US disclosed
EP-0359469-A2 An electroless plating-susceptive, fire retardant polyphenylene ether resin Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-03-21 EP disclosed
JP-S63215742-A PRODUCTION OF MICROPOROUS POLYPROPYLENE FILM TORAY IND INC 1988-09-08 JP disclosed