Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 10/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23983293 | 0.95 | KCNMA1 (0.42) | KCNMA1ELANEPDE9ACYP11B2USP14 | |
| SCHEMBL17570601 | 0.89 | CYP11B2 (0.40) | KCNMA1ELANEPDE9ACYP11B2KDM4E | |
| SCHEMBL22461722 | 0.84 | CYP11B2 (0.39) | KCNMA1ELANEPDE9ACYP11B2KDM4E | |
| SCHEMBL22461778 | 0.82 | KCNMA1 (0.38) | KCNMA1PDE9ACYP11B2KDM4ESMN1; SMN2 | |
| SCHEMBL23983368 | 0.82 | KCNMA1 (0.38) | KCNMA1PDE9ACYP11B2KDM4ESMN1; SMN2 | |
| SCHEMBL23984104 | 0.82 | KCNMA1 (0.38) | KCNMA1PDE9ACYP11B2KDM4ESMN1; SMN2 | |
| SCHEMBL17570641 | 0.81 | ELANE (0.40) | KCNMA1ELANEPDE9ACYP11B2USP14 | |
| SCHEMBL22461654 | 0.80 | CYP11B2 (0.39) | KCNMA1ELANEPDE9ACYP11B2KDM4E | |
| SCHEMBL21911771 | 0.80 | RECQL (0.38) | KCNMA1ELANEPDE9ACYP11B2KDM4E | |
| SCHEMBL21378003 | 0.77 | KDM4E (0.36) | KCNMA1PDE9ACYP11B2USP14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375785-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-10193079-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| EP-2976329-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | AOC3, AOC2, AOC1 | KCNMA1 1041/4885ELANE 232/4885PDE9A 3297/4885 |
| US-10193079-B2 | Materials for electronic devices | AOC3, AOC2, AOC1 | KCNMA1 1041/4885ELANE 232/4885PDE9A 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.