Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19434678 | 0.98 | MAOB (0.67) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL13673642 | 0.92 | MAOB (0.63) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL13673641 | 0.92 | MAOB (0.63) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL20878197 | 0.91 | MAOB (0.62) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7748759 | 0.87 | MAOB (0.74) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7748756 | 0.87 | MAOB (0.74) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL5703124 | 0.85 | MAOB (0.72) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL6522656 | 0.85 | MAOB (0.72) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL17560827 | 0.83 | MAOB (0.69) | MAOBNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL19449612 | 0.83 | MAOB (0.79) | MAOBNPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566012-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD (AU) | 2023-01-31 | — | — | US | disclosed |
| US-20220267258-A1 | ROBENIDINE ANALOGS AS POTENT ANTIMALARIALS AGAINST DRUG-RESISTANT PLASMODIUM FALCIPARUM | UNIV OREGON HEALTH & SCIENCE (US) | 2022-08-25 | — | — | US | disclosed |
| EP-3960729-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | Neoculi Pty Ltd (AU) | 2022-03-02 | — | — | EP | disclosed |
| EP-2991968-B1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2021-11-10 | — | — | EP | disclosed |
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-01-14 | — | — | US | disclosed |
| US-10829468-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-11-10 | — | — | US | disclosed |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-09-17 | — | — | US | disclosed |
| US-10752606-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-08-25 | — | — | US | disclosed |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
| US-10562880-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-02-18 | — | — | US | disclosed |
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2019-10-31 | — | — | US | disclosed |
| US-10392363-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2019-08-27 | — | — | US | disclosed |
| US-10370341-B2 | Compounds and methods of treating infections | NEOCULI PTY LTD (AU) | 2019-08-06 | — | — | US | disclosed |
| US-10253002-B2 | Compounds and methods of treating infections | NEOCULI PTY LTD (AU) | 2019-04-09 | — | — | US | disclosed |
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2019-03-21 | — | — | US | disclosed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | ELANE, IL1A, IL1B | MAOB 641/4885NPC1 813/4885RAB9A 3788/4885 |
| US-11566012-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-10370341-B2 | Compounds and methods of treating infections | ELANE, IL1A, IL1B | MAOB 641/4885NPC1 813/4885RAB9A 3788/4885 |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-10829468-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-10562880-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-10752606-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-20220267258-A1 | ROBENIDINE ANALOGS AS POTENT ANTIMALARIALS AGAINST DRUG-RESISTANT PLASMODIUM FALCIPARUM | CYP3A43, CYP2C9, CYP3A4 | MAOB 1072/4885NPC1 178/4885RAB9A 73/4885 |
| US-10392363-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAOB 1831/4885NPC1 282/4885RAB9A 3198/4885 |
| US-10253002-B2 | Compounds and methods of treating infections | ELANE, IL1A, IL1B | MAOB 641/4885NPC1 813/4885RAB9A 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.