Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705417 | 0.92 | QDPR (0.46) | MAP3K12CCR5QDPRTLR9TLR8 | |
| SCHEMBL12705251 | 0.86 | QDPR (0.52) | CCR5QDPRTLR9TLR8TLR7 | |
| SCHEMBL17580522 | 0.85 | CCR5 (0.39) | CCR5QDPRTLR9TLR8TLR7 | |
| SCHEMBL15283319 | 0.81 | HTR1A (0.44) | DRD2CCR5QDPRHTR1A | |
| SCHEMBL12705399 | 0.80 | SLC18A3 (0.48) | DRD2CCR5QDPRSLC18A3TLR9 | |
| SCHEMBL12705397 | 0.79 | QDPR (0.44) | QDPRSLC18A3TLR9TLR8TLR7 | |
| SCHEMBL12705532 | 0.78 | PDE4A (0.48) | CCR5PTGDRHTR1A | |
| SCHEMBL12705535 | 0.78 | CCR5 (0.47) | CCR5TLR9TLR8TLR7PTGDR | |
| SCHEMBL17580141 | 0.78 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BDRD2CCR5 | |
| SCHEMBL25780589 | 0.78 | SLC18A3 (0.46) | QDPRSLC18A3TLR9TLR7GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834248-B1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2016-03-16 | — | — | EP | disclosed |