Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.52 |
| ▸ | AMY2A | P04746 | 5/20 | 0.50 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.46 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271648 | 0.87 | XDH (0.40) | ALDH1A1CYP3A4MAPK1HSD17B10P4HB | |
| SCHEMBL4271653 | 0.87 | XDH (0.40) | ALDH1A1CYP3A4MAPK1HSD17B10P4HB | |
| SCHEMBL28151654 | 0.87 | XDH (0.40) | ALDH1A1CYP3A4MAPK1HSD17B10P4HB | |
| SCHEMBL27235 | 0.84 | AMY2A (0.62) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL10702505 | 0.84 | AMY2A (0.62) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL4264298 | 0.84 | AMY2A (0.62) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL24495313 | 0.84 | LGALS8 (0.56) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL12648833 | 0.84 | LGALS8 (0.56) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL12595429 | 0.84 | LGALS8 (0.56) | AMY1AAMY2ALGALS8LGALS3LGALS4 | |
| SCHEMBL16506646 | 0.84 | LGALS8 (0.56) | AMY1AAMY2ALGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334501-A1 | COMPOSITIONS INCLUDING AMPELOPSIS GROSSEDENTATA AND ALBIZIA JULIBRISSIN EXTRACTS AND METHODS OF USE | Johnson & Johnson Consumer Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
| EP-2605749-B1 | COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF | JOHNSON & JOHNSON CONSUMER INC (US) | 2017-11-22 | — | — | EP | disclosed |
| WO-2017030898-A1 | COMPOSITIONS INCLUDING AMPELOPSIS GROSSEDENTATA AND ALBIZIA JULIBRISSIN EXTRACTS AND METHODS OF USE | JOHNSON & JOHNSON CONSUMER INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| EP-2605748-B1 | USE OF COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS | JOHNSON & JOHNSON CONSUMER INC (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2605750-B1 | COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS FOR USE IN TREATING INFLAMMATION | JOHNSON & JOHNSON CONSUMER INC (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2605835-B1 | COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF | JOHNSON & JOHNSON CONSUMER (US) | 2016-03-16 | — | — | EP | disclosed |