Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL11287140 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL27726489 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL7998005 | 0.98 | ALDH1A1 (0.53) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL7161635 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL11029128 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1132384 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL2197455 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL48278 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL1503374 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 | |
| Trinitrophenol SCHEMBL653352 | 0.95 | ALDH1A1 (0.55) | ALDH1A1GPR35TDP1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118729885-A | Intelligent high-safety electronic detonator without initiating explosive, initiating explosive head and preparation process | 北京煋邦数码科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-116444325-B | Digital electronic detonator ignition agent and preparation method and application thereof | 无锡盛景微电子股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118239816-A | Ignition agent and application thereof | 湖北及安盾消防科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-109813188-B | Safe electronic ignition detonating piece and safe electronic ignition detonating detonator | 北京凯米迈克科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-113028918-B | Electronic ignition head and medicine dipping production process thereof | 南京雷芯聚力电子科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| WO-2024042390-A1 | SAFE INITIATION OF SHOCK TUBES (NONEL) CONNECTED TO MINERAL DETONATORS BASED ON NANOTECHNOLOGY | AYOMAN ESMAEIL (IR) | 2024-02-29 | — | — | WO | claimed |
| CN-117589018-A | High-temperature-resistant electronic detonator with vacuum heat insulation layer | 安徽理工大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117417221-A | Photosensitive ignition adhesive film, ignition cartridge adopting photosensitive ignition adhesive film and preparation method of ignition cartridge | 无锡盛景微电子股份有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116444325-A | Digital electronic detonator ignition agent and preparation method and application thereof | 无锡盛景微电子股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-218627979-U | High-energy ignition powder head device for long-delay electric detonator | 重庆顺安天力达爆破器材有限公司 | 2023-03-14 | — | — | CN | claimed |
| WO-1997040301-A1 | PYROTECHNIC DEVICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-10-30 | — | — | WO | claimed |
| CN-1031937-C | Method for preparing initiating explosive in casing | JIANGXI STEEL WIRE FACTORY (CN) | 1996-06-05 | — | — | CN | claimed |
| CN-1078965-A | A kind of method that in shell, prepares priming explosive | JIANGXI STEEL WIRE FACTORY (CN) | 1993-12-01 | — | — | CN | claimed |
| CN-85100858-B | Thermal bridge wire type high-temperature electric detonator | 北京工业学院 | 1988-09-21 | — | — | CN | claimed |
| CN-85100858-A | A kind of thermal bridge wire type high-temperature electric detonator | — | 1985-10-10 | — | — | CN | claimed |
| US-4455150-A | Chemically enhanced combustion of water-slurry fuels | OLEN KENNETH R | 1984-06-19 | — | — | US | claimed |
| US-4402268-A | Electric primer for caseless propellant charges | Usel, Hubert (AU) | 1983-09-06 | — | — | US | claimed |
| US-4316412-A | Low voltage nonprimary explosive detonator | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1982-02-23 | — | — | US | claimed |
| US-4213392-A | Electrically ignitable cartridge-less bullet | USEL HUBERT (AT) | 1980-07-22 | — | — | US | claimed |
| US-4145361-A | REACTING 2-FLUORO-2,2-DINITRO-ETHYL CHLOROFORMATE WITH AN ALKALI METAL PHENATE | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1979-03-20 | — | — | US | claimed |