Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039120 | 0.91 | POLB (0.58) | POLBKCNK9IMPDH2CYP2C9CYP3A4 | |
| SCHEMBL31164658 | 0.88 | L3MBTL1 (0.62) | POLBL3MBTL1 | |
| SCHEMBL12227206 | 0.82 | MAPT (0.66) | POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL3043849 | 0.82 | NPC1 (0.56) | KCNK9GAAIMPDH2SMN1; SMN2KCNK3 | |
| SCHEMBL3046746 | 0.82 | VNN1 (0.57) | KCNK9IMPDH2KCNK3CYP2C19 | |
| SCHEMBL3836272 | 0.82 | RAB9A (0.57) | POLBKCNK9IMPDH2L3MBTL1ROCK2 | |
| SCHEMBL10915368 | 0.81 | GAA (0.57) | GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL3838597 | 0.81 | IMPDH2 (0.52) | POLBIMPDH2SMN1; SMN2TACR3ROCK2 | |
| SCHEMBL94229 | 0.81 | IMPDH2 (0.52) | POLBKCNK9IMPDH2CYP2C9SMN1; SMN2 | |
| SCHEMBL3043303 | 0.80 | HDAC8 (0.61) | POLBIMPDH2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160074817-A1 | Halogen Resistant Amides, Polyamides, and Membranes Made From the Same | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) | 2016-03-17 | — | — | US | disclosed |