Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978103 | 0.85 | KDM4E (0.60) | KDM4EF2RL3NPC1RXRAGRIN1 | |
| SCHEMBL27681568 | 0.82 | ALDH1A1 (0.47) | — | |
| SCHEMBL3816388 | 0.79 | NNMT (0.48) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL29525223 | 0.79 | NNMT (0.48) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL31424084 | 0.77 | KDM4E (0.43) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL12073249 | 0.76 | CCR1 (0.43) | KDM4EF2RL3RXRAGRIN1GRIN2B | |
| SCHEMBL9061724 | 0.75 | RXFP1 (0.49) | KDM4EF2RL3NPC1RXRAGRIN1 | |
| SCHEMBL21651957 | 0.74 | FFAR1 (0.42) | KDM4EHCRTR1HCRTR2PIK3CA | |
| SCHEMBL24746481 | 0.74 | DAO (0.40) | KDM4ENPC1RXRAGRIN1GRIN2B | |
| SCHEMBL19753970 | 0.74 | RXRA (0.46) | KDM4EF2RL3RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9790222-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-9717729-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| US-9518053-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2016-08-25 | — | — | US | disclosed |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2016-03-17 | — | — | US | disclosed |
| CN-103201261-A | Lactam derivatives as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-07-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | ITGB5, ITGB1, ITGA5 | KDM4E 2577/4885F2RL3 49/4885NPC1 1009/4885 |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | KDM4E 2577/4885F2RL3 49/4885NPC1 1009/4885 |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | KDM4E 4044/4885F2RL3 332/4885NPC1 159/4885 |
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | KDM4E 4044/4885F2RL3 332/4885NPC1 159/4885 |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | KDM4E 4044/4885F2RL3 332/4885NPC1 159/4885 |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | KDM4E 2577/4885F2RL3 49/4885NPC1 1009/4885 |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | KDM4E 2577/4885F2RL3 49/4885NPC1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.