Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586253 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRNPSR1KDM4EMAPK1 | |
| SCHEMBL17586255 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRNPSR1KDM4EMAPK1 | |
| SCHEMBL13537143 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRNPSR1KDM4EMAPK1 | |
| SCHEMBL21452948 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRNPSR1KDM4EMAPK1 | |
| SCHEMBL17582309 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRNPSR1KDM4EMAPK1 | |
| SCHEMBL21064421 | 0.71 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4EMAPK1HIF1A | |
| SCHEMBL23992189 | 0.69 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4EMAPK1HIF1A | |
| SCHEMBL17586257 | 0.68 | ALDH1A1 (0.59) | ALDH1A1TSHRNPSR1HSD17B10 | |
| SCHEMBL13537157 | 0.68 | ALDH1A1 (0.40) | ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL31637913 | 0.67 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
| EP-3193855-B1 | BICYCLIC COMPOUNDS | RECURIUM IP HOLDINGS LLC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-10975035-B2 | Bicyclic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200270221-A1 | ANALGESIC COMPOUNDS | KTHERA, LLC | 2020-08-27 | — | — | US | disclosed |
| US-20190233377-A1 | BICYCLIC COMPOUNDS | Zeno Royalties & Milestones, LLC | 2019-08-01 | — | — | US | disclosed |
| US-10308609-B2 | Bicyclic compounds | Zeno Royalties & Milestones, LLC (US) | 2019-06-04 | — | — | US | disclosed |
| US-20160075654-A1 | BICYCLIC COMPOUNDS | RECURIUM IP HOLDINGS, LLC | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270221-A1 | ANALGESIC COMPOUNDS | INA, IK, ACHE | ALDH1A1 144/4885TSHR 3914/4885NPSR1 181/4885 |
| US-11242327-B2 | Analgesic compounds | INA, IK, ACHE | ALDH1A1 144/4885TSHR 3914/4885NPSR1 181/4885 |
| US-20190233377-A1 | BICYCLIC COMPOUNDS | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885NPSR1 62/4885 |
| US-20160075654-A1 | BICYCLIC COMPOUNDS | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885NPSR1 62/4885 |
| US-10975035-B2 | Bicyclic compounds | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885NPSR1 62/4885 |
| US-10308609-B2 | Bicyclic compounds | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885NPSR1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.