Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145929 | 0.98 | PKM (0.50) | PKMGRM1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5596073 | 0.88 | PKM (0.42) | PKM | |
| SCHEMBL12858204 | 0.86 | PKM (0.67) | PKMALDH1A1TSHRHSD17B10 | |
| SCHEMBL21002214 | 0.84 | PKM (0.48) | PKMGRM1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL22713155 | 0.82 | PKM (0.46) | PKMALDH1A1TSHRHSD17B10 | |
| SCHEMBL31493444 | 0.78 | GRM1 (0.35) | PKMGRM1 | |
| SCHEMBL4451716 | 0.78 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL17586294 | 0.77 | GRM1 (0.47) | PKMGRM1ALDH1A1TSHR | |
| SCHEMBL12858244 | 0.75 | GRM1 (0.45) | PKMGRM1ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL22553292 | 0.75 | POLB (0.38) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075654-A1 | BICYCLIC COMPOUNDS | RECURIUM IP HOLDINGS, LLC | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075654-A1 | BICYCLIC COMPOUNDS | OPRK1, OPRM1, OPRL1 | PKM 2397/4885GRM1 636/4885ALDH1A1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.