Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125504 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDTSHRKMT2AMEN1 | |
| SCHEMBL14829261 | 0.81 | MEN1 (0.67) | ALDH1A1HPGDTSHRKMT2AMEN1 | |
| SCHEMBL1758604 | 0.78 | HDAC6 (0.59) | ALDH1A1KMT2AMEN1HDAC10HDAC6 | |
| SCHEMBL3457076 | 0.76 | ALDH1A1 (0.65) | ALDH1A1POLBMAPTHPGDTSHR | |
| SCHEMBL19798449 | 0.74 | KMT2A (0.72) | ALDH1A1KMT2AMEN1SMN1; SMN2FAAH | |
| SCHEMBL20582511 | 0.73 | ATF4 (0.84) | ALDH1A1TSHRKMT2AMEN1ATF4 | |
| SCHEMBL4628600 | 0.73 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL3455269 | 0.72 | MEN1 (0.64) | ALDH1A1HPGDTSHRKMT2AMEN1 | |
| SCHEMBL13333544 | 0.72 | CNR2 (0.49) | ALDH1A1HPGDKMT2AMEN1CNR2 | |
| SCHEMBL19798759 | 0.72 | ALDH1A1 (0.68) | ALDH1A1POLBMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | claimed |
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |