Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798449 | 0.80 | KMT2A (0.72) | ALDH1A1KMT2AMEN1EPHX2NPC1 | |
| SCHEMBL12961980 | 0.78 | EPHX2 (0.62) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL4610298 | 0.77 | CNR2 (0.64) | ALDH1A1POLBEPHX2SMN1; SMN2 | |
| SCHEMBL19798759 | 0.77 | ALDH1A1 (0.68) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL1758671 | 0.73 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL13596196 | 0.71 | NPC1 (0.54) | ALDH1A1KMT2AMEN1EPHX2NPC1 | |
| SCHEMBL9334741 | 0.70 | TSHR (0.61) | ALDH1A1KMT2AMEN1EPHX2NPC1 | |
| SCHEMBL19807171 | 0.70 | KMT2A (0.56) | ALDH1A1KMT2AMEN1EPHX2NPC1 | |
| SCHEMBL13596178 | 0.70 | ADRB2 (0.59) | ALDH1A1POLBKMT2AMEN1EPHX2 | |
| SCHEMBL6565633 | 0.69 | HTT (0.49) | ALDH1A1POLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660437-B1 | HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF | AMOREPACIFIC CORP (KR) | 2008-10-15 | — | — | EP | claimed |