Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758874 | 0.85 | BCHE (0.45) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5667375 | 0.82 | APP (0.46) | KDM4EL3MBTL1MAPTHPGDRAB9A | |
| SCHEMBL1758876 | 0.80 | BCHE (0.46) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL12773272 | 0.78 | BCHE (0.46) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1638059 | 0.77 | MGAM (0.47) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1637949 | 0.77 | MAPK1 (0.46) | L3MBTL1RXRAMAPTMGAMGAA | |
| SCHEMBL1638070 | 0.77 | BCHE (0.50) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1759387 | 0.76 | FFAR1 (0.47) | BCHEKDM4EL3MBTL1MGAMGAA | |
| SCHEMBL3458384 | 0.76 | TDP1 (0.55) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL1639591 | 0.75 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493933-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056424-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |