Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.58 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946532 | 0.81 | F10 (0.59) | F10F2ABCB11ST14 | |
| SCHEMBL76883 | 0.81 | F10 (0.59) | F10F2ABCB11ST14 | |
| SCHEMBL3359664 | 0.79 | F10 (0.57) | F10F2ABCB11ST14 | |
| SCHEMBL15857721 | 0.79 | F10 (0.57) | F10F2ABCB11ST14 | |
| SCHEMBL20618506 | 0.78 | HDAC3 (0.58) | F10F2 | |
| SCHEMBL9170598 | 0.74 | NFKB1 (0.60) | — | |
| SCHEMBL24177659 | 0.74 | F10 (1.00) | F10F2ABCB11ST14 | |
| SCHEMBL13698655 | 0.74 | F10 (1.00) | F10F2ABCB11ST14 | |
| SCHEMBL77589 | 0.74 | F10 (1.00) | F10F2ABCB11ST14 | |
| SCHEMBL77993 | 0.73 | F10 (0.89) | F10F2ABCB11ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307407-B1 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD (KR) | 2016-03-16 | — | — | EP | disclosed |