Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76883 | 1.00 | F10 (0.59) | F10HPGDTSHRMAPK1F2 | |
| SCHEMBL13266061 | 0.82 | KMT2A (0.56) | F10HPGD | |
| SCHEMBL20618506 | 0.81 | HDAC3 (0.58) | F10HPGDTSHRMAPK1F2 | |
| SCHEMBL17588942 | 0.81 | F10 (0.58) | F10F2ABCB11ST14 | |
| SCHEMBL15857721 | 0.80 | F10 (0.57) | F10F2ABCB11ST14 | |
| SCHEMBL3359664 | 0.80 | F10 (0.57) | F10F2ABCB11ST14 | |
| SCHEMBL3233576 | 0.77 | F10 (0.38) | F10HPGDTSHRF2 | |
| SCHEMBL20615680 | 0.75 | HDAC3 (0.52) | F10HPGDTSHRMAPK1 | |
| SCHEMBL24177658 | 0.75 | F10 (0.66) | F10F2ABCB11ST14 | |
| SCHEMBL13698655 | 0.75 | F10 (1.00) | F10F2ABCB11ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451803-B1 | METHOD FOR PREPARING 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | GREEN CROSS CORP (KR) | 2017-12-27 | — | — | EP | claimed |
| US-8754210-B2 | Method for preparing 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl) derivative and intermediate used therein | GREEN CROSS CORPORATION (KR) | 2014-06-17 | — | — | US | claimed |
| US-20120136149-A1 | METHOD FOR PREPARING 5-CHLORO-N-(METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | LEGOCHEM BIOSCIENCE LTD. (KR) | 2012-05-31 | — | — | US | claimed |
| EP-2451803-A2 | METHOD FOR PREPARING 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | Green Cross Corporation (KR) | 2012-05-16 | — | — | EP | claimed |
| WO-2011005029-A2 | METHOD FOR PREPARING 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | GREEN CROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | claimed |
| EP-2451803-B1 | METHOD FOR PREPARING 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | GREEN CROSS CORP (KR) | 2017-12-27 | — | — | EP | disclosed |
| EP-2451803-B1 | METHOD FOR PREPARING 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | GREEN CROSS CORP (KR) | 2017-12-27 | — | — | EP | disclosed |
| EP-2837628-B1 | METHOD FOR PREPARING RIVAROXABAN INTERMEDIATE | CHINA NAT MEDICINES GUORUI PHARMACEUTICAL CO LTD (CN) | 2016-11-30 | — | — | EP | disclosed |
| US-20150299160-A1 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
| US-20150299160-A1 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
| US-20150299160-A1 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
| US-9079892-B2 | Method for preparing rivaroxaban intermediate | CHINA NATIONAL MEDICINES GUORUI PHARMACEUTICAL CO., LTD. (CN) | 2015-07-14 | — | — | US | disclosed |
| WO-2008155033-A1 | SUBSTITUTED (OXAZOLIDINON-5-YL-METHYL) -2-THIOPHENE-CARBOXAMIDES AND USE THEREOF IN THE FIELD OF BLOOD COAGULATION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-24 | — | — | WO | disclosed |
| EP-1874764-A2 | IMINO-OXAZOLIDINES AND USE THEREOF AS ANTICOAGULANTS | Bayer HealthCare AG (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007051532-A1 | PHENYLENEBISOXAZOLIDINE DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | BAYER HEALTHCARE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
| US-20070066615-A1 | Heterocyclic compounds | BAYER HEATHCARE AG (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066615-A1 | Heterocyclic compounds | BAYER HEATHCARE AG (DE) | 2007-03-22 | — | — | US | disclosed |
| WO-2006111285-A2 | IMINO-OXAZOLIDINES AND USE THEREOF AS ANTICOAGULANTS | BAYER HEALTHCARE AG (DE) | 2006-10-26 | — | — | WO | disclosed |
| EP-1626969-A1 | HETEROCYCLIC COMPOUNDS | Bayer HealthCare AG (DE) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004101557-A1 | HETEROCYCLIC COMPOUNDS | BAYER HEALTHCARE AG (DE) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136149-A1 | METHOD FOR PREPARING 5-CHLORO-N-(METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN | TFPI, F2, F9 | F10 20/4885HPGD 1181/4885TSHR 1517/4885 |
| US-20150299160-A1 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | VKORC1, CYP3A4, TFPI | F10 35/4885HPGD 144/4885TSHR 2502/4885 |
| US-20070066615-A1 | Heterocyclic compounds | F2, SERPINC1, TFPI | F10 12/4885HPGD 25/4885TSHR 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.