Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20496665 | 1.00 | MEN1 (0.37) | MEN1KMT2AFBP1NR1I2NPC1 | |
| SCHEMBL13754063 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNACYP3A4NOS3NOS2 | |
| SCHEMBL20496664 | 0.74 | CYP1A2 (0.38) | MEN1KMT2ANR1I2NPC1RAB9A | |
| SCHEMBL10824109 | 0.74 | LMNA (0.37) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL4057730 | 0.71 | ALDH1A1 (0.38) | KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL17777983 | 0.70 | KMT2A (0.45) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6546668 | 0.70 | LMNA (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6546664 | 0.70 | LMNA (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5317035 | 0.70 | LMNA (0.33) | ALDH1A1LMNACYP3A4NOS3NOS2 | |
| SCHEMBL5317773 | 0.70 | ASAH1 (0.40) | NPC1RAB9AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334297-B2 | Chiral imidazolium salts for asymmetric catalysis | NORTHWESTERN UNIVERSITY (US) | 2016-05-10 | — | — | US | disclosed |
| US-20160075728-A1 | Chiral Imidazolium Salts for Asymmetric Catalysis | NATIONAL SCIENCE FOUNDATION | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075728-A1 | Chiral Imidazolium Salts for Asymmetric Catalysis | NDC1, NUDC, NIT2 | MEN1 1085/4885KMT2A 1176/4885FBP1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.