Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501527 | 0.75 | SIGMAR1 (0.45) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL4082756 | 0.68 | TAAR1 (0.37) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL4079143 | 0.68 | SIGMAR1 (0.37) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL4077458 | 0.68 | SIGMAR1 (0.37) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL2700588 | 0.67 | SIGMAR1 (0.52) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL3340543 | 0.66 | SMN1; SMN2 (0.43) | MEN1KMT2A | |
| Amphetamine SCHEMBL28331167 | 0.66 | TAAR1 (0.68) | TAAR1SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3340550 | 0.66 | SIGMAR1 (0.42) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL115878 | 0.65 | TAAR1 (0.40) | TRPA1TAAR1MEN1KMT2AMMP8 | |
| SCHEMBL109030 | 0.63 | TAAR1 (0.58) | TRPA1TAAR1MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875074-B1 | ORGANOSILOXANE COMPOSITIONS | DOW SILICONES CORP (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-2155804-B1 | A METHOD FOR MAKING PHENYLALKYLSILOXANES | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | disclosed |
| US-9567503-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2017-02-14 | — | — | US | disclosed |
| US-20150175863-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2015-06-25 | — | — | US | disclosed |
| EP-2875074-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014013038-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2493984-A2 | PAINTABLE ELASTOMER | Dow Corning Corporation (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2493985-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120214925-A1 | Organosiloxane Compositions | DOW CORNING CORPORATION (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214902-A1 | Paintable Elastomer | DOW CORNING EUROPE SA (BE) | 2012-08-23 | — | — | US | disclosed |
| WO-2011051173-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051236-A2 | PAINTABLE ELASTOMER | DOW CORNING CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |
| US-20100255224-A1 | Sealant For Insulating Glass Unit | DOW CORNING EUROPE SA (BE) | 2010-10-07 | — | — | US | disclosed |
| EP-2167771-A1 | SEALANT FOR INSULATING GLASS UNIT | Dow Corning Corporation (US) | 2010-03-31 | — | — | EP | disclosed |
| EP-2155804-A1 | A METHOD FOR MAKING PHENYLALKYLSILOXANES | Dow Corning Corporation (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009013309-A1 | MOISTURE CURING ELASTOMER COMPOSITIONS | DOW CORNING CORPORATION (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009013308-A1 | SEALANT FOR INSULATING GLASS UNIT | DOW CORNING CORPORATION (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2008152042-A1 | A METHOD FOR MAKING PHENYLALKYLSILOXANES | DOW CORNING CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |
| EP-0304958-B1 | Room temperature-curable organopolysiloxane composition | TORAY SILICONE CO (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0304958-A2 | Room temperature-curable organopolysiloxane composition | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |