SCHEMBL17589552

SCHEMBL17589552

c1ccc(-c2ccc(-c3c4ccccc4c(-c4cc5ccccc5c5c4oc4cc6ccccc6cc45)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MPI P34949 1/20 0.39
ALOX5 P09917 1/20 0.38
RECQL P46063 1/20 0.37
MAOB P27338 1/20 0.37
RAB9A P51151 1/20 0.37
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
FYN P06241 1/20 0.36
MAPK3 P27361 1/20 0.36
AHR P35869 1/20 0.36
PAX8 Q06710 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
ESR1 P03372 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17737528 0.92 MEN1 (0.37) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL19080125 0.91 MEN1 (0.35) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL17589557 0.88 CYP11B1 (0.50) GPR84KMT2AKDM4EALOX5MAOB
SCHEMBL17589550 0.88 GPR84 (0.40) GPR84MEN1KMT2AALDH1A1MAPT
SCHEMBL17737570 0.86 ALOX5 (0.40) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL17589543 0.86 ALOX5 (0.36) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL17737531 0.86 KDM4E (0.41) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL17589551 0.85 GPR84 (0.43) GPR84MEN1KMT2AKDM4EALOX5
SCHEMBL17737578 0.85 GPR84 (0.41) GPR84MEN1KMT2AALDH1A1MAPT
SCHEMBL18817812 0.85 MEN1 (0.33) GPR84MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9899611-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-20 US disclosed
US-9899611-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-20 US disclosed
US-20160079546-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160079546-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 GPR84 2500/4885MEN1 465/4885KMT2A 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.