Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | GSK3B | P49841 | 6/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1293480 | 0.82 | PTPN1 (0.68) | PTPN1GSK3BPLAU | |
| SCHEMBL4307699 | 0.82 | GSK3B (0.52) | PTPN1GSK3B | |
| SCHEMBL753074 | 0.77 | GSK3B (0.50) | PTPN1GSK3B | |
| SCHEMBL1758852 | 0.77 | GSK3B (0.42) | PTPN1GSK3BERN1 | |
| SCHEMBL11482012 | 0.75 | PTPN1 (0.84) | PTPN1GSK3BPLAU | |
| SCHEMBL27944525 | 0.74 | UTS2R (0.43) | UTS2RERN1 | |
| SCHEMBL1758869 | 0.73 | PLAU (0.36) | PTPN1UTS2RERN1PLAUFFAR1 | |
| SCHEMBL15114347 | 0.72 | PTPN1 (0.78) | PTPN1GSK3B | |
| SCHEMBL579790 | 0.72 | ACP3 (0.31) | — | |
| SCHEMBL1440680 | 0.72 | ACP3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499127-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | disclosed |
| EP-2499115-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011059887-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011059850-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |