Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.59 |
| ▸ | SDHB | P21912 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | STAT1 | P42224 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676169 | 0.89 | KMO (0.47) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL30122726 | 0.85 | SDHB (0.47) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL7001627 | 0.83 | MAPK13 (0.50) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL18963 | 0.83 | NPSR1 (0.49) | SDHBNPSR1LMNASTAT3RAB9A | |
| SCHEMBL5593061 | 0.82 | SDHB (0.68) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL3569045 | 0.81 | SDHB (0.76) | SDHBNPSR1LMNASTAT3RAB9A | |
| SCHEMBL7215386 | 0.81 | MAPK11 (0.61) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL8666474 | 0.80 | SDHB (0.56) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL14561097 | 0.80 | MAPT (0.44) | KMOSDHBNPSR1LMNASTAT3 | |
| SCHEMBL5823023 | 0.80 | CDC7 (0.44) | KMOSDHBNPSR1LMNASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |