Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA3 | P07451 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615549 | 0.91 | KMT2A (0.46) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL1759048 | 0.91 | KMT2A (0.46) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL30865768 | 0.89 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL19127566 | 0.86 | CA1 (0.47) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL10615554 | 0.84 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10615596 | 0.84 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1759087 | 0.84 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27767684 | 0.83 | PRMT5 (0.61) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL1759109 | 0.83 | CA2 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL368915 | 0.83 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924203-A | Method for synthesizing ozagrel intermediate | 山东新时代药业有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20160015838-A1 | Vinylsulfone-based 18F-labeling Compositions and Methods and Uses Thereof | UNIVERSITY OF SOUTHERN CALIFORNIA USC STEVENS (US) | 2016-01-21 | — | — | US | disclosed |
| US-9017645-B2 | Homoglutamic acid derivatives | PIRAMAL IMAGING SA (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20130071327-A1 | HOMOGLUTAMIC ACID DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-03-21 | — | — | US | disclosed |
| EP-2499113-A1 | HOMOGLUTAMIC ACID DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011057986-A1 | HOMOGLUTAMIC ACID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-19 | — | — | WO | disclosed |
| EP-2322500-A1 | Fluoro-labeled homo-glutamate derivatives and precursors thereof | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2322514-A1 | Homoglutamic acid and glutamic acid derivatives | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015838-A1 | Vinylsulfone-based 18F-labeling Compositions and Methods and Uses Thereof | TST, VARS1, STS | TSHR 161/4885CA1 3847/4885CA2 4778/4885 |
| US-20130071327-A1 | HOMOGLUTAMIC ACID DERIVATIVES | FGB, GGCT, RIMKLA | TSHR 3658/4885CA1 551/4885CA2 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.