Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468379 | 0.81 | ELANE (0.41) | MAOAMAOBNAAAADRA1ASLC6A3 | |
| SCHEMBL17592809 | 0.80 | CYP3A4 (0.34) | — | |
| SCHEMBL17593127 | 0.80 | ELANE (0.50) | MAOAMAOBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL22728644 | 0.77 | GAA (0.38) | GAAL3MBTL1NAAAHDAC3MAPK1 | |
| SCHEMBL11742230 | 0.74 | L3MBTL1 (0.41) | GAAL3MBTL1 | |
| SCHEMBL16736246 | 0.73 | HSD17B10 (0.38) | — | |
| SCHEMBL22728634 | 0.72 | HTR7 (0.41) | NAAAADRA1ASLC6A3 | |
| SCHEMBL22914872 | 0.70 | GAA (0.43) | GAAL3MBTL1 | |
| SCHEMBL6380088 | 0.70 | MAOA (0.42) | MAOAMAOBL3MBTL1SMN1; SMN2GSK3B | |
| SCHEMBL17550624 | 0.68 | RAB9A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | claimed |
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2019-06-04 | — | — | US | claimed |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| EP-3191533-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | claimed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| US-11021617-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10703842-B2 | Encapsulated polymerization initiators, polymerization systems and methods using the same | SIRRUS, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200190369-A1 | 1,1 DISUBSTITUTED ALKENE COMPOUND BASED PRESSURE SENSITIVE ADHESIVES | SIRRUS, INC. | 2020-06-18 | — | — | US | disclosed |
| US-20190263955-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. | 2019-08-29 | — | — | US | disclosed |
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-20170247490-A1 | ENCAPSULATED POLYMERIZATION INITIATORS, POLYMERIZATION SYSTEMS AND METHODS USING THE SAME | SIRRUS, INC. | 2017-08-31 | — | — | US | disclosed |
| EP-3191533-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9683147-B2 | Encapsulated polymerization initiators, polymerization systems and methods using the same | SIRRUS, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| WO-2016195817-A1 | ENCAPSULATED POLYMERIZATION INITIATORS, POLYMERIZATION SYSTEMS AND METHODS USING THE SAME | SIRRUS, INC. (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20160347976-A1 | ENCAPSULATED POLYMERIZATION INITIATORS, POLYMERIZATION SYSTEMS AND METHODS USING THE SAME | SIRRUS, INC. | 2016-12-01 | — | — | US | disclosed |
| US-9334430-B1 | Encapsulated polymerization initiators, polymerization systems and methods using the same | SIRRUS, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263955-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | PCBP1, PARG, PARP1 | MAOA 2532/4885MAOB 3053/4885GAA 1306/4885 |
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | PCBP1, PARG, PARP1 | MAOA 2654/4885MAOB 3091/4885GAA 1196/4885 |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | PCBP1, PARG, PARP1 | MAOA 2654/4885MAOB 3091/4885GAA 1196/4885 |
| US-11021617-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | PCBP1, PARG, PARP1 | MAOA 2532/4885MAOB 3053/4885GAA 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.