Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24759386 | 0.86 | KMT2A (0.49) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL19295399 | 0.83 | KMT2A (0.56) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL255260 | 0.80 | SNCA (0.58) | MAPTSNCAALDH1A1POLB | |
| SCHEMBL26354026 | 0.80 | KMT2A (0.52) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL31469962 | 0.78 | HTT (0.48) | KMT2AALOX5MAPTGAAMEN1 | |
| SCHEMBL26355082 | 0.77 | ALOX5 (0.79) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL12649366 | 0.77 | ALOX5 (0.68) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL19554277 | 0.76 | HTR2A (0.54) | KMT2APKMMAPTGAASNCA | |
| SCHEMBL542043 | 0.75 | KMT2A (0.84) | KMT2APKMALOX5MAPTGAA | |
| SCHEMBL4951809 | 0.75 | KMT2A (0.84) | KMT2APKMALOX5MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348430-A1 | MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID | RAMOT AT TEL AVIV UNlVERSITY LTD. (IL) | 2017-12-07 | — | — | US | disclosed |
| US-20170245492-A1 | AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS | RAMOT AT TEL AVIV UNlVERSITY LTD. (IL) | 2017-08-31 | — | — | US | disclosed |
| EP-3190880-A1 | AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS | Ramot at Tel-Aviv University Ltd. (IL) | 2017-07-19 | — | — | EP | disclosed |
| EP-3191137-A1 | MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID | Ramot at Tel-Aviv University Ltd. (IL) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038596-A1 | AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-03-17 | — | — | WO | disclosed |
| WO-2016038595-A1 | MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348430-A1 | MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID | KIT, JMJD7, LIPA | KMT2A 2723/4885PKM 919/4885ALOX5 2698/4885 |
| US-20170245492-A1 | AGROCHEMICAL DELIVERY SYSTEM BASED ON ENZYME- OR pH- RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRIDS | APEH, JMJD7, AGL | KMT2A 1015/4885PKM 850/4885ALOX5 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.