Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748767 | 0.83 | ALDH1A1 (0.57) | SNCAMAPTLMNAPTGS2MAOB | |
| SCHEMBL2641474 | 0.83 | LMNA (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19616330 | 0.82 | SNCA (0.45) | SNCACA12CA1CA2CA7 | |
| SCHEMBL2061312 | 0.81 | KCNH2 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10900784 | 0.81 | LMNA (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22430913 | 0.81 | HTR2A (0.63) | SNCACA12CA1CA2CA7 | |
| SCHEMBL17595133 | 0.80 | KMT2A (0.52) | SNCAMAPTALDH1A1POLB | |
| SCHEMBL3997879 | 0.80 | SNCA (0.56) | SNCAMAPTLMNAMAOBALDH1A1 | |
| SCHEMBL5704167 | 0.79 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15863990 | 0.79 | LMNA (0.47) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104973999-A | Novel method for preparing allene by cesium hydroxide catalysis | UNIV HUNAN | 2015-10-14 | — | — | CN | claimed |
| CN-100554251-C | A kind of maleimide derivatives and preparation method thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-1896058-A | Maleimide derivative and its preparation | CHINESE ACAD INST CHEMISTRY (CN) | 2007-01-17 | — | — | CN | claimed |
| US-20240208898-A1 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240208898-A1 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| EP-4313013-A2 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117279629-A | Enamine N-oxide: synthesis and use in hypoxia responsive prodrugs and imaging agents | 达纳－法伯癌症研究所公司 | 2023-12-22 | — | — | CN | disclosed |
| US-11827628-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827628-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-116768806-A | Substituted 1,2, 3-triazole compound, preparation method thereof and application thereof in preventing and treating plant diseases | 中国农业大学 | 2023-09-19 | — | — | CN | disclosed |
| US-11667611-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20040058058-A1 | Prefatory anti-forgery protection and consecutive machine-assisted authentication of genuine documents and other values | SHCHEGOLIKHIN ALEXANDER NIKITO (RU) | 2004-03-25 | — | — | US | disclosed |
| EP-1385637-A1 | IMPROVED RAMAN-ACTIVE TAGGANTS AND THEIR RECOGNITION | Quantag Systems, Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002085543-A1 | IMPROVED RAMAN-ACTIVE TAGGANTS AND THEIR RECOGNITION | QUANTAG SYSTEMS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-4581315-A | COATING SUBSTRATE WITH IRRADIATION POLYMERIZABLE DIACETYLINIC CONJUGATED MATERIAL | UNIVERSITY PATENTS, INC. (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0077577-B1 | PHOTOGRAPHIC ARTICLES COMPRISING A COMPOUND HAVING ACETYLENIC BONDS AND METHODS FOR PRODUCING THE ARTICLES | UNIVERSITY PATENTS, INC. (US) | 1985-12-04 | — | — | EP | disclosed |
| EP-0022618-B1 | PHOTOGRAPHIC OR PHOTOLITHOGRAPHIC ARTICLE AND METHOD OF FORMING A PHOTORESIST | UNIVERSITY PATENTS, INC. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4439514-A | Photoresistive compositions | UNIVERSITY PATENTS, INC. (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0077577-A2 | Photographic articles comprising a compound having acetylenic bonds and methods for producing the articles | UNIVERSITY PATENTS, INC. (US) | 1983-04-27 | — | — | EP | disclosed |
| EP-0022618-A2 | Photographic or photolithographic article and method of forming a photoresist | UNIVERSITY PATENTS, INC. (US) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667611-B2 | Compositions and methods for inhibition of the JAK pathway | JAK3, JAK2, JAK1 | SNCA 3721/4885CA12 4660/4885CA1 4805/4885 |
| US-11827628-B2 | Compositions and methods for inhibition of the JAK pathway | JAK3, JAK2, JAK1 | SNCA 3627/4885CA12 4598/4885CA1 4788/4885 |
| US-20240208898-A1 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | ENO1, HIF1A, HIF1AN | SNCA 1961/4885CA12 326/4885CA1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.