Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744890 | 0.71 | AKR1B1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL10741438 | 0.70 | SHBG (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL17595406 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDPOLBSMN1; SMN2MEN1 | |
| SCHEMBL9049816 | 0.70 | RAB9A (0.64) | ALDH1A1HPGDPOLBSMN1; SMN2MEN1 | |
| SCHEMBL4821398 | 0.69 | ADRA1D (0.47) | SMN1; SMN2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL18437365 | 0.69 | HPGD (0.50) | ALDH1A1HPGDPOLBSMN1; SMN2ESR2 | |
| SCHEMBL7353467 | 0.68 | HPGD (0.60) | ALDH1A1HPGDPOLBSMN1; SMN2ESR2 | |
| SCHEMBL1515733 | 0.68 | HPGD (0.57) | ALDH1A1HPGDPOLBSMN1; SMN2ESR1 | |
| SCHEMBL31478201 | 0.68 | MEN1 (0.60) | ALDH1A1HPGDPOLBSMN1; SMN2MEN1 | |
| SCHEMBL17595498 | 0.68 | SMN1; SMN2 (0.39) | ALDH1A1HPGDPOLBSMN1; SMN2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040180-A1 | 3-(1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2016-03-17 | — | — | WO | claimed |