Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596170 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDNPSR1KMT2A | |
| SCHEMBL17596158 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL17596451 | 0.86 | MEN1 (0.50) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL17595923 | 0.85 | TDP1 (0.47) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL17595555 | 0.81 | KMT2A (0.39) | ALDH1A1KDM4EHPGDNPSR1SLC40A1 | |
| SCHEMBL17595553 | 0.78 | POLB (0.47) | KDM4EHPGDTDP1KMT2AMEN1 | |
| SCHEMBL12020192 | 0.74 | KDM4E (0.55) | ALDH1A1KDM4EHPGDNPSR1SLC40A1 | |
| SCHEMBL17596177 | 0.74 | NPC1 (0.42) | ALDH1A1KDM4ETDP1SLC40A1KMT2A | |
| SCHEMBL24338474 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4ETDP1SLC40A1KMT2A | |
| SCHEMBL9945608 | 0.73 | KDM4E (0.57) | ALDH1A1KDM4EHPGDNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715425-B | Herbicidal quinolines | 先正达参股股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3191465-B1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-19 | — | — | EP | disclosed |
| US-9980486-B2 | Herbicidal quinolines | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170251670-A1 | HERBICIDAL QUINOLINES | NQO2, DDT, ATP1B1 | ALDH1A1 33/4885KDM4E 1955/4885HPGD 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.