Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596128 | 0.91 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ENPSR1MEN1 | |
| SCHEMBL17596158 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ELMNANPSR1 | |
| SCHEMBL17595555 | 0.82 | KMT2A (0.39) | ALDH1A1HPGDKDM4ENPSR1MEN1 | |
| SCHEMBL17595556 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAALOX12DHODH | |
| SCHEMBL17595920 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ELMNAALOX12 | |
| SCHEMBL17595553 | 0.79 | POLB (0.47) | HPGDKDM4ELMNAMEN1KMT2A | |
| SCHEMBL17596451 | 0.79 | MEN1 (0.50) | ALDH1A1HPGDKDM4ENPSR1MEN1 | |
| SCHEMBL17596120 | 0.78 | L3MBTL1 (0.50) | ALDH1A1KDM4ELMNAALOX12DHODH | |
| SCHEMBL17595923 | 0.78 | TDP1 (0.47) | ALDH1A1HPGDKDM4ENPSR1MEN1 | |
| SCHEMBL13255421 | 0.77 | DHODH (0.52) | ALDH1A1KDM4ELMNAALOX12DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715425-B | Herbicidal quinolines | 先正达参股股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3191465-B1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-19 | — | — | EP | disclosed |
| US-9980486-B2 | Herbicidal quinolines | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170251670-A1 | HERBICIDAL QUINOLINES | NQO2, DDT, ATP1B1 | ALDH1A1 33/4885HPGD 2552/4885KDM4E 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.