SCHEMBL17596451

SCHEMBL17596451

COC(=O)c1cc2cccnc2c(-c2ccccc2)c1O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
KDM4E B2RXH2 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 4/20 0.46
EGLN1 Q9GZT9 6/20 0.45
SLC40A1 Q9NP59 1/20 0.45
ALOX15 P16050 1/20 0.43
HTT P42858 1/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
AXL P30530 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17595923 0.86 TDP1 (0.47) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL17596128 0.86 ALDH1A1 (0.58) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL17596170 0.79 ALDH1A1 (0.47) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL29046675 0.75 KDM4E (0.55) MAPTKDM4ETDP1ALDH1A1EGLN1
SCHEMBL17596177 0.75 NPC1 (0.42) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL17596158 0.75 ALDH1A1 (0.47) MEN1KMT2AMAPTKDM4ETDP1
SCHEMBL24338474 0.74 KDM4E (0.50) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL9945608 0.74 KDM4E (0.57) MEN1KMT2AMAPTKDM4ETDP1
SCHEMBL31086278 0.74 PDE4A (0.56) MAPTALDH1A1EGLN1SLC40A1ALOX15
SCHEMBL14255189 0.74 KDM4E (0.53) MEN1KMT2AMAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715425-B Herbicidal quinolines 先正达参股股份有限公司 2020-11-06 CN disclosed
EP-3191465-B1 HERBICIDAL QUINOLINES SYNGENTA PARTICIPATIONS AG (CH) 2018-12-19 EP disclosed
US-9980486-B2 Herbicidal quinolines SYNGENTA PARTICIPATIONS AG (CH) 2018-05-29 US disclosed
US-20170251670-A1 HERBICIDAL QUINOLINES SYNGENTA PARTICIPATIONS AG (CH) 2017-09-07 US disclosed
EP-3191465-A1 HERBICIDAL QUINOLINES Syngenta Participations AG (CH) 2017-07-19 EP disclosed
CN-106715425-A Herbicidal quinolines 先正达参股股份有限公司 2017-05-24 CN disclosed
WO-2016038173-A1 HERBICIDAL QUINOLINES SYNGENTA PARTICIPATIONS AG (CH) 2016-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170251670-A1 HERBICIDAL QUINOLINES NQO2, DDT, ATP1B1 MEN1 1355/4885KMT2A 522/4885MAPT 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.