Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596123 | 0.85 | NPC1 (0.40) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL17596566 | 0.82 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DCYP2C9 | |
| SCHEMBL17596505 | 0.77 | MEN1 (0.38) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL17596175 | 0.76 | POLB (0.42) | ATRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17596608 | 0.75 | L3MBTL1 (0.40) | PDE4APDE4BPDE4CPDE4DCYP2C9 | |
| SCHEMBL17595555 | 0.75 | KMT2A (0.39) | PDE4AKDM4EALDH1A1MAPT | |
| SCHEMBL17596182 | 0.75 | KMT2A (0.37) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL17596559 | 0.65 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL17596177 | 0.65 | NPC1 (0.42) | KDM4EALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL619560 | 0.59 | HTT (0.51) | CYP2C9KDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |