Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596505 | 0.85 | MEN1 (0.38) | KMT2AMEN1PDE4APDE4BPDE4D | |
| SCHEMBL17595555 | 0.84 | KMT2A (0.39) | KMT2AMEN1NPC1PDE4AEGLN1 | |
| SCHEMBL17596608 | 0.84 | L3MBTL1 (0.40) | PDE4APDE4BPDE4DPDE4CEGLN1 | |
| SCHEMBL17596566 | 0.83 | PDE4A (0.37) | KMT2AMEN1PDE4APDE4BPDE4D | |
| SCHEMBL17596123 | 0.82 | NPC1 (0.40) | KMT2AMEN1NPC1PDE4APDE4B | |
| SCHEMBL17595920 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1NPC1PDE4APDE4B | |
| SCHEMBL17596178 | 0.75 | ATR (0.39) | PDE4APDE4BPDE4DPDE4CL3MBTL1 | |
| SCHEMBL17596180 | 0.75 | POLB (0.47) | KMT2AMEN1NPC1EGLN1KDR | |
| SCHEMBL17596451 | 0.66 | MEN1 (0.50) | KMT2AMEN1EGLN1AXLL3MBTL1 | |
| SCHEMBL17596170 | 0.66 | ALDH1A1 (0.47) | KMT2AMEN1PDE4APDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |