Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596505 | 0.85 | MEN1 (0.38) | L3MBTL1EGLN1PTPN6PTPN11PLK4 | |
| SCHEMBL17596182 | 0.84 | KMT2A (0.37) | L3MBTL1EGLN1PLK4MAP4K4EGFR | |
| SCHEMBL17595555 | 0.84 | KMT2A (0.39) | EGLN1PDE4A | |
| SCHEMBL17596566 | 0.83 | PDE4A (0.37) | EGLN1CYP2C9PDE4APDE4BPDE4C | |
| SCHEMBL17596120 | 0.80 | L3MBTL1 (0.50) | L3MBTL1TOP1UBE2NEGLN1CYP1A2 | |
| SCHEMBL17596123 | 0.76 | NPC1 (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17596178 | 0.75 | ATR (0.39) | L3MBTL1CYP2C9PDE4APDE4BPDE4C | |
| SCHEMBL17596190 | 0.75 | POLB (0.47) | L3MBTL1EGLN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17596186 | 0.74 | ALDH1A1 (0.46) | L3MBTL1TOP1CYP1A2CYP2C9 | |
| SCHEMBL17596451 | 0.66 | MEN1 (0.50) | L3MBTL1EGLN1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |