Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596178 | 0.85 | ATR (0.39) | PDE4APDE4BPDE4DPDE4CLMNA | |
| SCHEMBL17596182 | 0.82 | KMT2A (0.37) | NPC1KMT2AMEN1PDE4APDE4B | |
| SCHEMBL17596559 | 0.81 | PDE4A (0.43) | NPC1KMT2AMEN1PDE4APDE4B | |
| SCHEMBL17596177 | 0.80 | NPC1 (0.42) | NPC1KMT2AMEN1RAB9A | |
| SCHEMBL17596505 | 0.78 | MEN1 (0.38) | KMT2AMEN1PDE4APDE4BPDE4D | |
| SCHEMBL17595555 | 0.76 | KMT2A (0.39) | NPC1KMT2AMEN1RAB9APDE4A | |
| SCHEMBL17596608 | 0.76 | L3MBTL1 (0.40) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL17596122 | 0.76 | POLB (0.43) | NPC1KMT2AMEN1RAB9APDE4A | |
| SCHEMBL17596566 | 0.75 | PDE4A (0.37) | KMT2AMEN1PDE4APDE4BPDE4D | |
| SCHEMBL17596188 | 0.69 | PDE4A (0.41) | NPC1KMT2AMEN1RAB9APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |