Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596177 | 0.86 | NPC1 (0.42) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17596559 | 0.75 | PDE4A (0.43) | PDE4ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL17596451 | 0.72 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17595923 | 0.71 | TDP1 (0.47) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17596128 | 0.71 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL17596123 | 0.69 | NPC1 (0.40) | PDE4ANPC1MEN1KMT2ARAB9A | |
| SCHEMBL24338474 | 0.68 | KDM4E (0.50) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5749934 | 0.67 | TDP1 (0.72) | MEN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL14820334 | 0.66 | KMT2A (0.53) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL17595920 | 0.66 | ALDH1A1 (0.44) | PDE4ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |