Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597319 | 0.85 | ALDH1A1 (0.43) | FFAR4MAPTALDH1A1 | |
| SCHEMBL17597287 | 0.80 | PPARG (0.40) | DRD2DRD3FFAR4METAP2PPARG | |
| SCHEMBL17597419 | 0.77 | CA12 (0.37) | FFAR4METAP2PPARGGRM5CA12 | |
| SCHEMBL17597937 | 0.77 | PPARG (0.34) | FFAR4METAP2EGLN2EGLN1PPARG | |
| SCHEMBL17432054 | 0.77 | LMNA (0.43) | DRD2DRD3FFAR4METAP2EGLN2 | |
| SCHEMBL17597733 | 0.76 | ALDH1A1 (0.43) | DRD2DRD3MAPTGRM5ALDH1A1 | |
| Bromide SCHEMBL17423756 | 0.76 | LMNA (0.43) | DRD2DRD3FFAR4METAP2EGLN2 | |
| SCHEMBL17597779 | 0.75 | CA12 (0.38) | FFAR4METAP2PPARGCA12CA1 | |
| SCHEMBL17597543 | 0.75 | ALDH1A1 (0.41) | MAPTCA12CA1CA2CA3 | |
| SCHEMBL17597515 | 0.75 | ALDH1A1 (0.43) | FFAR4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040764-A1 | CARBONYL LINKED BICYCLIC HETEROARYL N-BENZIMIDAZOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS | SPERO THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |