Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4116244 | 0.93 | NAAA (0.59) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL6979898 | 0.91 | — | — | |
| SCHEMBL28448079 | 0.88 | NAAA (0.59) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL31069916 | 0.84 | NAAA (0.71) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL15155946 | 0.84 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL207015 | 0.83 | NAAA (0.64) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL11921056 | 0.83 | NAAA (0.65) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL31069906 | 0.82 | NAAA (0.75) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL258780 | 0.81 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL31069913 | 0.81 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191445-B1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-12 | — | — | EP | disclosed |
| US-10023519-B2 | Cyclobutane containing carboxylic acid GPR120 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170247311-A1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-08-31 | — | — | US | disclosed |
| EP-3191445-A1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | Bristol-Myers Squibb Company (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016040223-A1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023519-B2 | Cyclobutane containing carboxylic acid GPR120 modulators | GPR68, GPR88, GPR55 | NAAA 2647/4885CYP2C19 1960/4885SMN1; SMN2 4643/4885 |
| US-20170247311-A1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | GPR68, GPR88, GPR55 | NAAA 2647/4885CYP2C19 1960/4885SMN1; SMN2 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.