Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707674 | 1.00 | DRD2 (0.46) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL1670919 | 1.00 | DRD2 (0.46) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL24456007 | 0.95 | BTK (0.47) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL3901760 | 0.95 | BTK (0.47) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL1498385 | 0.87 | DRD2 (0.45) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL1498493 | 0.87 | DRD2 (0.45) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL1498384 | 0.87 | DRD2 (0.45) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL21107181 | 0.86 | DRD2 (0.40) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL21070900 | 0.86 | DRD2 (0.40) | DRD2DRD3BTKEPHX1KDM1A | |
| SCHEMBL21071389 | 0.86 | DRD2 (0.40) | DRD2DRD3BTKEPHX1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995617-B1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | SHANGHAI INST PHARMACEUTICAL IND (CN) | 2018-01-31 | — | — | EP | disclosed |
| US-9550741-B2 | Benzoisothiazole compounds and methods of treating schizophrenia | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2017-01-24 | — | — | US | disclosed |
| US-20160096811-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | SHANAGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-04-07 | — | — | US | disclosed |
| EP-2995617-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | Shanghai Institute of Pharmaceutical Industry (CN) | 2016-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096811-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | HTR3A, SLC6A3, HTR5A | DRD2 10/4885DRD3 5/4885BTK 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.