Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 1.00 |
| ▸ | DRD2 | P14416 | 20/20 | 1.00 |
| ▸ | HTR2A | P28223 | 20/20 | 1.00 |
| ▸ | DRD3 | P35462 | 11/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809060 | 1.00 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL19809053 | 0.96 | HTR1A (0.93) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL17598572 | 0.96 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL17598625 | 0.91 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL17598631 | 0.91 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL19824708 | 0.91 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL17598649 | 0.90 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL17598577 | 0.90 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL19824743 | 0.90 | HTR1A (1.00) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL19809048 | 0.89 | HTR1A (0.80) | HTR1ADRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995617-B1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | SHANGHAI INST PHARMACEUTICAL IND (CN) | 2018-01-31 | — | — | EP | disclosed |
| US-9550741-B2 | Benzoisothiazole compounds and methods of treating schizophrenia | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2017-01-24 | — | — | US | disclosed |
| US-20160096811-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | SHANAGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-04-07 | — | — | US | disclosed |
| EP-2995617-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | Shanghai Institute of Pharmaceutical Industry (CN) | 2016-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096811-A1 | BENZOISOTHIAZOLE COMPOUNDS AND USE IN PREPARATION OF ANTIPSYCHOTIC DRUGS | HTR3A, SLC6A3, HTR5A | HTR1A 11/4885DRD2 10/4885HTR2A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.