Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965294 | 0.90 | POLB (0.56) | KMT2APOLBHTT | |
| SCHEMBL17599014 | 0.84 | MEN1 (0.49) | KMT2AMEN1HTTMAPTADRB2 | |
| SCHEMBL27978752 | 0.77 | RAB9A (0.58) | KMT2AMEN1HTTADRB3 | |
| SCHEMBL17599008 | 0.76 | KMT2A (0.77) | KMT2AMEN1POLBHTT | |
| SCHEMBL14965405 | 0.75 | — | — | |
| SCHEMBL14965217 | 0.74 | ADRB2 (0.62) | KMT2AMEN1HTTMAPTADRB2 | |
| SCHEMBL4430810 | 0.74 | MEN1 (0.66) | KMT2AMEN1HTTMAPTADRB2 | |
| SCHEMBL14965453 | 0.72 | ADRB2 (0.61) | KMT2AMEN1HTTMAPTADRB2 | |
| SCHEMBL27978708 | 0.71 | KMT2A (0.49) | KMT2AMEN1 | |
| SCHEMBL16293337 | 0.71 | MEN1 (0.55) | KMT2AMEN1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290511-B2 | Thieno-pyrimidines, useful as potassium channel inhibitors | XENTION LIMITED (GB) | 2016-03-22 | — | — | US | disclosed |