Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197400 | 0.82 | MAPT (0.50) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1030525 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL17599750 | 0.80 | MEN1 (0.51) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL27641771 | 0.79 | GAA (0.56) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL28862177 | 0.76 | DRD2 (0.46) | ALDH1A1KDM4EMEN1KMT2ADRD2 | |
| SCHEMBL1815031 | 0.76 | DRD2 (0.46) | ALDH1A1KDM4EMEN1KMT2ADRD2 | |
| SCHEMBL6197027 | 0.76 | MAPT (0.50) | ALDH1A1POLBGAAMAPTMAPK1 | |
| SCHEMBL5544703 | 0.76 | CTSB (0.54) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL16513522 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBKDM4EGAAMEN1 | |
| SCHEMBL27770383 | 0.74 | DRD2 (0.43) | ALDH1A1KDM4EMEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091527-B1 | SULFIDE, SULFOXIDE AND SULFONE CHALCONE ANALOGUES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2016-03-23 | — | — | EP | disclosed |