Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034952 | 0.90 | — | — | |
| SCHEMBL12647615 | 0.88 | PGR (0.32) | PGRPDK2 | |
| SCHEMBL5013191 | 0.84 | PDK2 (0.42) | PGRPDK2ALKAKR1A1AKR1B1 | |
| SCHEMBL29294792 | 0.84 | PDK2 (0.42) | PGRPDK2ALKAKR1A1AKR1B1 | |
| SCHEMBL29458875 | 0.84 | PDK2 (0.42) | PGRPDK2ALKAKR1A1AKR1B1 | |
| SCHEMBL5063493 | 0.84 | PDK2 (0.42) | PGRPDK2ALKAKR1A1AKR1B1 | |
| SCHEMBL31363096 | 0.82 | PDK2 (0.41) | PGRPDK2 | |
| SCHEMBL204806 | 0.80 | PDK2 (0.44) | PGRPDK2AKR1A1AKR1B1 | |
| SCHEMBL29403081 | 0.80 | PDK2 (0.44) | PGRPDK2AKR1A1AKR1B1 | |
| SCHEMBL29587737 | 0.80 | PDK2 (0.44) | PGRPDK2AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| WO-2011057701-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011057701-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | PIEZO1, EMC1, EPCAM | PGR 1576/4885PDK2 1366/4885ALK 3665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.