Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19104482 | 0.94 | MAPT (0.33) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL16978534 | 0.94 | MAPT (0.33) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL15625655 | 0.94 | MAPT (0.33) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL12647627 | 0.94 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL15625656 | 0.94 | KDM4E (0.35) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1079319 | 0.92 | MAPT (0.34) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL18505534 | 0.92 | CAMK2D (0.32) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL16978541 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL19104580 | 0.91 | KDM4E (0.30) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL2603593 | 0.90 | CAMK2D (0.32) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| WO-2011057701-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011057701-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | PIEZO1, EMC1, EPCAM | KDM4E 3460/4885ALDH1A1 62/4885HPGD 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.