SCHEMBL1760713

SCHEMBL1760713

COc1cc2c(cc1OC)C(C)N(C)CC2

nearest known ligand 0.97

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.97
KCNN2 Q9H2S1 4/20 0.63
KCNN3 Q9UGI6 4/20 0.63
KCNN1 Q92952 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.61
CA7 P43166 1/20 0.60
BRD4 O60885 2/20 0.59
LMNA P02545 2/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
HSD17B10 Q99714 2/20 0.57
MAPK1 P28482 1/20 0.57
CYP2D6 P10635 1/20 0.57
ALOX15 P16050 1/20 0.53
RAD52 P43351 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19888927 1.00 MAOA (0.97) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL29382740 1.00 MAOA (0.97) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL18256759 0.89 MAOA (0.77) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL24039929 0.87 MAOA (0.75) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL14739491 0.87 MAOA (0.86) MAOAMAPK1
SCHEMBL26956106 0.87 MAOA (0.75) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL8034415 0.87 MAOA (0.97) MAOASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL27156518 0.87 MAOA (0.75) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL29515907 0.87 MAOA (0.75) MAOAKCNN2KCNN3KCNN1SMN1; SMN2
SCHEMBL21255942 0.86 MAOA (0.72) MAOAKCNN2KCNN3KCNN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
CN-113157912-A Text classification method based on machine learning 航天科工网络信息发展有限公司 2021-07-23 CN disclosed
US-20200299130-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. (US) 2020-09-24 US disclosed
US-9902699-B2 Synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes Gregory Rosocha (CA) 2018-02-27 US disclosed
CN-104561007-A Lymantria dispar linnaeus CYP6B53 gene dsRNA and application thereof in nuisanceless control UNIV NORTHEAST FORESTRY 2015-04-29 CN disclosed
US-20110114075-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. 2011-05-19 US disclosed
EP-2318307-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR Blacklight Power, Inc. (US) 2011-05-11 EP disclosed
WO-2010014684-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BLACKLIGHT POWER, INC. (US) 2010-02-04 WO disclosed
EP-2119434-A1 Use of heterosidic flavonoid derivatives for therapy of stem cell cancers INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2009-11-18 EP disclosed
US-5272270-A Process for the preparation of 1-alkylisoquinoline derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 MAOA 1925/4885KCNN2 252/4885KCNN3 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.