Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17607309 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CES2FAAHCES1TSHR | |
| SCHEMBL17607311 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CES2FAAHCES1TSHR | |
| SCHEMBL8922141 | 0.98 | ALDH1A1 (0.39) | ALDH1A1CES2FAAHCES1TSHR | |
| SCHEMBL1415144 | 0.92 | ALDH1A1 (0.40) | ALDH1A1CES2FAAHCES1 | |
| SCHEMBL29290134 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CES2 | |
| SCHEMBL1516643 | 0.89 | CETP (0.36) | ALDH1A1TDP1 | |
| SCHEMBL11138230 | 0.86 | GPR84 (0.40) | ALDH1A1CES2CES1TSHRGPR84 | |
| SCHEMBL8369532 | 0.85 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL31547 | 0.84 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL110882 | 0.83 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016043771-A9 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016043771-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | FAAH2, CNR1, TAS2R5 | ALDH1A1 190/4885CES2 176/4885FAAH 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.